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eVOC Ontologies v2.6

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Recent Changes to eVOC

Three new cDNA libraries were added in eVOC 2.6:

  • cDNA Clone of a Human Placenta
  • NIH_MGC_258
  • Oleic acid SSH Library

eVOC 2.5 saw numerous term name clean ups and a few term additions. See the eVOC 2.5 release notes for details.


Summary of eVOC v2.6

The data mapped was taken from Genbank release 144 (October 15, 2004) and includes cumulative updates up until January 4, 2005.

Ontology Numbers of Terms Annotated cDNA Libraries1
Anatomical System 396 7840 (93%)
Associated With 24 0 (0%)3
Cell Type 166 658 (8%)2
Development Stage 155 6833 (81%)
Experimental Technique 28 8395 (100%)
Microarray Platform 19 8395 (100%)4
Pathology 178 7090 (84%)
Pooling 9 8155 (97%)
Tissue Preparation 8 6969 (83%)
Treatment 24 0 (0%)3

Total number of annotated cDNA libraries: 8392

Notes:

  1. All cDNA libraries are mapped to each ontology but are only considered annotated if they are mapped to terms other than unclassifiable or pending.
  2. Many cDNA libraries are not annotated with specific cell type information and are therefore mapped to unclassifiable.
  3. Mapping of the cDNA libraries to the Associated With and Treatment ontologies is work currently being undertaken by the Electric Genetics Evoke team - the unannotated cDNA libraries are associated with the term pending in these two ontologies.
  4. cDNA library data is mapped to term not applicable in the Microarray Platform ontology.


Download eVOC v2.6 Ontologies

Two flavours of the eVOC ontologies are available for download - annotated and unannotated. The annotated versions list the cDNAs annotated to each term. The unannotated versions contain just the ontology terms. Each download contains all ten ontologies.

All the available data sets (ESTs, Unigene clusters, H-inv clusters, etc) are mapped to the ontology terms via the cDNAs. Thus if you're downloading data you probably want to get an annotated copy of the ontologies (otherwise you won't be able to connect the data to the ontology terms).

If you're wanting to view the ontologies in DagEdit you'll need the GO or OBO format. Unfortunately neither of these formats currently support annotations.

If you have Protege and its OWL plugin, you can download the OWL versions of the ontologies which do contain the cDNA annotations. You can also use the OWL version in COBrA.

Ontologies:

  • eVOC tab-delimited flatfile format [1] (18K)
  • GO flatfile format [2] (12K)
  • OBO file format [3] (14K)

Annotated Ontologies:

  • eVOC tab-delimited flatfile format [4] (707K)1
  • OWL format [5] (936K)
  • HTML format [6] (647K)

File Format Documentation:

The file format documentation is now available as part of the eVOContology.org site. You can find it here.

Notes:

  1. The eVOC tab-delimited flatfile used to include the data file containing the EST to cDNA mappings. This file is now available on the data download page and so is not included here.

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Page last modified on February 21, 2005, at 04:47 PM