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eVOC Contributors

History

The eVOC orthogonal controlled vocabulary is one of several projects funded by a grant from the South African Department of Arts, Culture, Science, and Technology's highly competitive Innovation Fund Program. Awarded in 1998 to SANBI in collaboration with Electric Genetics the grant project, entitled Human Disease: a genomic perspective, aims to relate phenotype to the genome using transcript or gene expression data.

eVOC achieves this crucial link between the DNA sequences and expression phenotype information by describing the location and timing of gene expression and allowing the assessment of tissue expression profiles, differential gene expression levels and the physical distribution of expression across the genome. eVOC's unique and innovative untangled ontologies provide extremely powerful and intuitive querying and results analysis.

Several collaborations have since spawned with groups actively working with ontologies and the study of human disease including Imperial College of Science, Technology and Medicine, Oxford University, The Wellcome Trust Sanger Institute (Ensembl) and the Swiss Institute for Bioinformatics. SANBI is also currently co-ordinating with the Gene Ontology consortium and distributes the eVOC data free of charge to the community.

Electric Genetics has developed a commercial product, evoke, that integrates with eVOC and provides additional mappings, curation, browsing, querying and analysis functionalities.

Contributors

A large number of people from several organisations have contributed to the development and refinement of eVOC and to the annotation of expression data using the eVOC ontologies: